Top 13 Venture Capital Firms in San Diego, California

• 7 min read
Top 13 Venture Capital Firms in San Diego, California

Individual entrepreneurs and even talented founders although performing well at their companies would become even better when partnered with relaibale and promising venture capitals. These venture capitals can offer you good investment, some even offer long-term services. They will not only provide you capital but also business management approach, resources and easy access to extensive networks of entrepreneurs, founders, executives and investors that may bring your business on top of the leader board.

San Diego is not only a home of entrepeneurs and founders most particularly in life sciences, health and technology-based services, but the city also has been a hotspot for capitalists since 2018.  In fact, despite the impact of pandemic, they still made a record breaking investments and vc firms will continue to flow in the region for the next coming years. As long as local startups continue to emerge and seek financial support to VC firms in the region, they will never stop on growing and investing.

Top 13 Venture Capital Firms in Sand Diego, California

Venture capital investment across California is at high record breaking levels, since the region is fueled by a strong stock market that’s adaptive and open to initial public stock offerings for companies operating in diffent sectors. Below are some of the leading venture capital firms in the city that you may opt for.

Avalon Ventures

Avalon Ventures is a venture capital and private equity headquartered in San Diego Area, West Coast and the Western United States. They are mainly interested in offering early-stage and seed-stage venture capital funds to companies operating primarily in California and the Northeast. In particular, they seek to invest within information technology, life sciences wireless communications and Web 3.0 digital media.

They believe that the most challenging and rewarding period of company creation is funding. Their team is composed of former individual entrepreneurs and professionals helping dedicated founders and executives to create disruptive ideas and build transformative companies in the everchanging market. Since its founding year, it has been funding companies and providing other business strategies to cultivate tomorrow's life science breakthroughs.

Bootstrap Ventures

Bootstrap Venture Partner is an investment fund and private equity firm funding early-stage technology-enabled companies that deliver products and services with high value and have a meaningful impact on the community.

They partner with well-driven and like-minded entrepreneurs and founders, just as driven as their whole team to establish new and promising companies that are making a huge difference in different fields such as Artificial Intelligence and EdTech. The VC firm also backs up companies operating in the big data, B2B service, clean energy, data analytics, healthcare, life science, media,  software, and outsourcing sectors.

Since its inception, the VC firm has been providing funds and mentoring to great businesses that can bring effective and efficient solutions to the emerging real-world problems of the industry.

Domain Associates

Domain Associates is one of the first venture capital and private equity firms. It was founded in 1985 with the goal to exclusively provide funds to companies engaged in the life sciences, biotechnology and healthcare sector. They specialize in early-stage ventures, late-stage ventures, and private equity.

Since its inception, Domain has raised eight funds and has been involved in the establishment and success of more than 260 companies and managed to raise more than $2.8 billion in capital funds. Currently, the VC firm is considered a proven healthcare venture capital leader in San Diego, CA with high investment returns from the portfolio companies they built to bring innovations to human health sectors.

Enterprise Partners Venture Capital

Enterprise Partners Venture Capital is an investment fund and private equity firm interested in early-stage and late-stage investment ventures. The VC firm prefers to backup emerging companies primarily those located in Southern California. In particular, they fund businesses operating within the life sciences and technology sectors with a great focus on new technology fields including consumer products and applications, digital media, digital home technologies and services, specialized energy and materials, and wireless networks. Whereas, they invest in later-stage companies, and buyout opportunities on a case-by-case basis.

Currently, they are offering their sixth fund and have built more than 150 companies in California with more than $1.1 billion investment.

Finistere Ventures

Finistere Ventures is a global investment fund partner and private equity firm that seeks to invest in the agriculture and life sciences sector. They are headquartered in the Bay Area and San Diego with offices in different areas like Israel, Australia, New Zealand, the Gulf states and South East Asia.

They are investing in agricultural technology to improve productivity and sustainability in food,  alternative energy crops, animal health, novel Ag production systems, and the precision in Ag subsectors.

Since its founding year, they have provided growth capital to their portfolio companies and helped them bring advancements and transformation to food and agriculture sector. Also, with their strong partnerships with major Ag technology and Food supply chain companies in the market, they were able to provide their portfolio companies with easy access and insight to large proprietary networks of entreprenuers and founders in the industry.

Forward Ventures

Forward Ventures is a leading venture capital and private equity firm based in San Diego, California. The VC firm specializes in all stages of development and growth investment but most of their recent fund primarily focuses on biopharmaceutical products in early clinical development. They are interested in investing in emerging companies operating within the biological sciences, healthcare, life science, medical device and pharmaceutical sectors. Usually, they invest across the United States and has the potential to offer capital funds to European companies.

Since it was founded in 1993, the firm has invested in more than 50 companies and currently has more than $500 million in capital under management.

Hamilton BioVentures

Hamilton BioVentures is a venture capital and private equity company providing funds to  talented and promising individual entrepreneurs bringing innovations to Life Science technology market. Particularly, they back up companies operating in therapeutic medical devices/technology, and biotechnology platforms with great focus on drug development, drug delivery and therapeutic biomaterials sectors.

They have over $100 million investment under management. Hamilton BioVentures investments generally categorized a direct equity and being offered to early-stage companies based on the West Coast.

In particular, the VC firm backup companies that have developing better treatments such as biopharmaceuticals and medical devices for major human illnesses and other medical conditions.

HCAP Partners

HCAP Partners formerly known as Huntington Capital is a California-based private equity and investment fund firm founded in 2000. The VC firm is providing growth capital and mentoring to lower middle market companies in California and the Western United States.

It was founded with a goal to transform the economic well-being of communities while generating and formulating above-market rate returns. Due to their credibility and legacy in the venture capital field, HCAP Partners was recognized as one of the leaders in the fast growing area of debt and equity “impact” funds.

Currently, HCAP Partners is operating two limited partnerships: Huntington Capital, LP, a federally licensed Small Business Investment Company (SBIC), and Huntington Capital Fund II, LP an institutional limited partnership.

Mission Ventures

Mission Ventures is a California-based venture capital firm providing investment and business coaching to early-stage companies in emerging markets with side mission to create superior returns on investment for its investors. The VC firm targets those entrepreneurial companies located in Southern California. They have specialization in seed, early-stage and growth capital investments in high-growing companies in software and information technology sectors across California. Particularly, they prefer to provide investments in communications, enterprise applications, enterprise applications, infrastructure, mobile, and technology-driven services.

In addition to capital, they also share entrepreneurial experience, brings management talents, and mentoring to the most outstanding and revolutionary founders and individual entrepreneurs in the region.

Shepherd Ventures

Shepherd Ventures is an investment fund and private equity headquartered in San Diego. It is part of Southern California's Tech Coast. The VC firm an easy access to other technology-based companies across the region. They highly focus on information technology founded and operated by committed and well-experienced management teams with extraordinary value propositions and high potential of growth in the industry. Particularly, their team invests in  communications infrastructure, components, networking, digital media, enterprise applications, information systems, internet, semiconductors, software, and wireless mobile computing sectors.

Since its founding year, the only interest of the team are those startups and companies based in Southern California and the Southwest, particularly in San Diego, where venture capital firms are not prominent and emerging. Their ultimate goal is to make significant capital appreciation through a well-balanced and picked portfolio of early and later-stage equity companies.

Sorrento Ventures

Sorrento Ventures is a private equity and investment fund company interested in providing enough capital and substantial vision to extraordinary high-growth companies. Most of their investment funds are highly focus  on medical devices and biotechnology, communications, enterprise software,  electronics and hardware, and other enabling distribution technologies including the internet and specialty retail. Currently, they managed to carry over $115,000,000 capital under management and has successfully backup more than 40 companies for the last fifteen years.

Sorrento Ventures is run by well-experienced management teams with well-structured approaches and business management, Since their inception, they have proven that they can bring many promising companies on top of the market leader board.

TVC Capital

TVC Capital is an investment fund and operator led growth equity firm based in San Diego, CA. The VC firm is highly focused on investments in and acquisitions of compelling growth stage B2B software companies. They are providing their portfolio companies with capital, mentoring, resources, and easy access to huge networks of entrepreneurs and investors. TVC Capital firm prefers to backup companies operating in the digital health, fintech, software, and software-enabled service sectors.

Since 2007, they are partnering and collaborating with exceptional management teams and investors to speed up the growth, and maximize the value of their portfolio companies transforming them into global market leaders.

Winward Ventures

Windward Ventures is a venture capital and private equity based in San Diego, California with presence on the British Virgin Islands. They are interested in providing capital, guidance and sources to early-stage and high-growth companies across Southern California. The VC firm was established in 1997 with the objective to provide management services and help their portfolio companies reach their full potentials in their niche.

Since that time it was established, they have been committed to assisting and investing in more than 25 companies. Windward Ventures specializes in Cloud Management, Enterprise Software Early-stage and Late-stage Venture Capital.

Key Takeaways

With all these leading venture capitals, San Diego can build a better name for itself, especially with the help of other venture capitalists outside the region. There might be few VC firms but all of them are good deals and once you qualified in their team, it would be easier for you to scale your business and reach your full potentials in your niche.

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